Life would be tragic if it weren't funny.
Interview 'The Science of Second-Guessing', The New York Times (2004)
It is a waste of time to be angry about my disability. One has to get on with life and I haven't done badly. People won't have time for you if you are always angry or complaining.
Quoted in 'Return of the time lord', The Guardian (2005)
My expectations were reduced to zero when I was 21. Everything since then has been a bonus.
Interview 'The Science of Second-Guessing', The New York Times (2004)
We are just an advanced breed of monkeys on a minor planet of a very average star. But we can understand the Universe. That makes us something very special.
Interview in Der Spiegel (1988)
So next time someone complains that you have made a mistake, tell him that may be a good thing. Because without imperfection, neither you nor I would exist.
Into the Universe with Stephen Hawking, Discovery Channel (2010)
Remember to look up at the stars and not down at your feet.
Widely quoted from his public talks; exact first source not confirmed